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Symbol Name ID |
Cd38
CD38 antigen MGI:107474 |
| Darker colors indicate more annotations |
| Human Phenotypes | Autoimmunity |
| Disease(s) Associated with CD38 | |
| type 1 diabetes mellitus |
| Mouse Phenotypes | increased T cell apoptosis |
abnormal thymus morphology |
enlarged thymus |
insulitis |
enlarged spleen |
increased NK cell number |
decreased CD4-positive, CD25-positive, alpha-beta regulatory T cell number |
decreased CD4-positive, alpha-beta T cell number |
increased effector memory CD8-positive, alpha-beta T cell number |
decreased memory-marker CD4-positive NK T cell number |
decreased CD4-positive NK T cell number |
decreased NK T cell number |
decreased effector memory T-helper cell number |
decreased T-helper cell number |
abnormal spleen morphology |
abnormal humoral immune response |
increased susceptibility to autoimmune diabetes |
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| Availability | Mouse Genotype | |||||||||||||||||
| Cd38em1(IMPC)Ccpcz/Cd38em1(IMPC)Ccpcz | ||||||||||||||||||
| Cd38tm1Lnd/Cd38tm1Lnd | ||||||||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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